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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-formyl peptide receptor 2
Species	Homo sapiens (Human)
Gene	FPR2
Synonym	FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor LXA4 receptor LXA4R FPR2A FPR2/ALX Fpr-rs2 ALX ALX/FPR2 ALXR FMLP-R-I FMLP-related receptor I FMLPX formyl peptide receptor 2 formyl peptide receptor, related sequence 2 Formyl peptide receptor-like 1 RFP [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
UniProt	P25090
Protein Data Bank	N/A
GPCR-HGmod model	P25090
3D structure model	This predicted structure model is from GPCR-EXP P25090.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4227
IUPHAR	223
DrugBank	N/A

Ligand

Name	UNM000003607801
Molecular formula	C18H18N2O4S
IUPAC name	N-(furan-2-ylmethyl)-N-quinolin-8-ylsulfonylbutanamide
Molecular weight	358.412
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.5
Synonyms	AKOS001780537 N-(2-furfuryl)-N-(8-quinolylsulfonyl)butyramide CHEMBL1394724 N-(furan-2-ylmethyl)-N-quinolin-8-ylsulfonylbutanamide MolPort-000-631-638 BDBM40447 N-(2-furylmethyl)-N-(quinolin-8-ylsulfonyl)butanamide cid_6458050 AC1O5H9E N-(2-furanylmethyl)-N-(8-quinolinylsulfonyl)butanamide N-(furan-2-ylmethyl)-N-quinolin-8-ylsulfonyl-butanamide MCULE-2550836022 ZINC5234885 [ Show all ]
Inchi Key	CQDBTSUEPCZFCJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18N2O4S/c1-2-6-17(21)20(13-15-9-5-12-24-15)25(22,23)16-10-3-7-14-8-4-11-19-18(14)16/h3-5,7-12H,2,6,13H2,1H3
PubChem CID	6458050
ChEMBL	CHEMBL1394724
IUPHAR	N/A
BindingDB	40447
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<40300.0 nM	N/A	BindingDB

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