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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H2 receptor
Species	Mus musculus (Mouse)
Gene	Hrh2
Synonym	Gastric receptor I H2 receptor H2R HH2R
Disease	N/A for non-human GPCRs
Length	397
Amino acid sequence	MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQLFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTRLSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA
UniProt	P97292
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2245
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	103827-18-5
Molecular formula	C16H30N4O
IUPAC name	N-butyl-6-[2-(1H-imidazol-5-yl)ethylamino]heptanamide
Molecular weight	294.443
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.9
Synonyms	AKOS030602723 CTK0D8330 N-Butyl-6-{[2-(1H-imidazol-5-yl)ethyl]amino}heptanamide DTXSID30553559 ACMC-20m6mp CHEMBL306864 Heptanamide, N-butyl-6-[[2-(1H-imidazol-4-yl)ethyl]amino]- [ Show all ]
Inchi Key	ZNEWKFPYDSIEPE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H30N4O/c1-3-4-10-19-16(21)8-6-5-7-14(2)18-11-9-15-12-17-13-20-15/h12-14,18H,3-11H2,1-2H3,(H,17,20)(H,19,21)
PubChem CID	13974548
ChEMBL	CHEMBL306864
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Relative potency	0.0 -	PMID2959777	ChEMBL

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