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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Neuromedin-U receptor 2
Species	Homo sapiens (Human)
Gene	NMUR2
Synonym	G-protein coupled receptor FM-4 G-protein coupled receptor TGR-1 FM4 NMU-R2 NMU2 receptor FM-4 SNORF72 TGR-1 [ Show all ]
Disease	N/A
Length	415
Amino acid sequence	MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPAALSSEQMSRTNYQSFHFNKT
UniProt	Q9GZQ4
Protein Data Bank	N/A
GPCR-HGmod model	Q9GZQ4
3D structure model	This predicted structure model is from GPCR-EXP Q9GZQ4.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075144
IUPHAR	299
DrugBank	N/A

Ligand

Name	CHEMBL3343016
Molecular formula	C16H11FO4
IUPAC name	2-(2-fluoro-5-methoxyphenyl)-3-hydroxychromen-4-one
Molecular weight	286.258
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BDBM50102657
Inchi Key	QMTVLYLMGFKYPA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H11FO4/c1-20-9-6-7-12(17)11(8-9)16-15(19)14(18)10-4-2-3-5-13(10)21-16/h2-8,19H,1H3
PubChem CID	118716780
ChEMBL	CHEMBL3343016
IUPHAR	N/A
BindingDB	50102657
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	253000.0 nM	PMID25262941	BindingDB,ChEMBL

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