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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H2 receptor
Species	Mus musculus (Mouse)
Gene	Hrh2
Synonym	Gastric receptor I H2 receptor H2R HH2R
Disease	N/A for non-human GPCRs
Length	397
Amino acid sequence	MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQLFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTRLSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA
UniProt	P97292
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2245
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL421482
Molecular formula	C17H24N4O
IUPAC name	4-[2-(1H-imidazol-5-yl)ethylamino]-N-(4-methylphenyl)pentanamide
Molecular weight	300.406
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.9
Synonyms	N/A
Inchi Key	PMHVAECKAAOWIJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H24N4O/c1-13-3-6-15(7-4-13)21-17(22)8-5-14(2)19-10-9-16-11-18-12-20-16/h3-4,6-7,11-12,14,19H,5,8-10H2,1-2H3,(H,18,20)(H,21,22)
PubChem CID	13974532
ChEMBL	CHEMBL421482
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Relative potency	0.0 -	PMID2959777	ChEMBL

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