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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostacyclin receptor
Species	Rattus norvegicus (Rat)
Gene	Ptgir
Synonym	PGI receptor PGI2 receptor IP receptor prostacyclin receptor prostaglandin I2 (prostacyclin) receptor (IP) prostaglandin I2 receptor prostanoid IP receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	416
Amino acid sequence	MVASGGRPDGPPSITPESPLIVGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSPQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLCHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTGIMAVCSLPLTIRGFTQAIAPDSREMGDLHAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQTPLSRPVSGRRDTLAPDSLQAKEGNWVPLSTWGTGQVAPLTAVPLSGGDGCSVGMPSKTEAVVACSLC
UniProt	P43253
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3322
IUPHAR	345
DrugBank	N/A

Ligand

Name	CHEMBL3398213
Molecular formula	C30H28N2O5
IUPAC name	2-[[6-[[3-(3-methoxyphenyl)-6-oxo-4-phenylpyridazin-1-yl]methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid
Molecular weight	496.563
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50103437
Inchi Key	OWEFAHHFPDBJGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H28N2O5/c1-36-24-11-5-10-23(16-24)30-26(21-7-3-2-4-8-21)17-28(33)32(31-30)18-20-13-14-25-22(15-20)9-6-12-27(25)37-19-29(34)35/h2-12,16-17,20H,13-15,18-19H2,1H3,(H,34,35)
PubChem CID	118727292
ChEMBL	CHEMBL3398213
IUPHAR	N/A
BindingDB	50103437
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<10000.0 nM	PMID25666818	BindingDB,ChEMBL

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