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GPCR

NameHistamine H2 receptor
SpeciesMus musculus (Mouse)
GeneHrh2
SynonymGastric receptor I
H2 receptor
H2R
HH2R
DiseaseN/A for non-human GPCRs
Length397
Amino acid sequenceMEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQLFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTRLSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA
UniProtP97292
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2245
IUPHARN/A
DrugBankN/A

Ligand

Name1H-Imidazole-5-ethanamine, N-(1-methylhexyl)-
Molecular formulaC12H23N3
IUPAC nameN-[2-(1H-imidazol-5-yl)ethyl]heptan-2-amine
Molecular weight209.337
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP2.6
SynonymsCHEMBL66949
AKOS014565202
103827-11-8
Inchi KeyNOTOMXGHDLEQBF-UHFFFAOYSA-N
Inchi IDInChI=1S/C12H23N3/c1-3-4-5-6-11(2)14-8-7-12-9-13-10-15-12/h9-11,14H,3-8H2,1-2H3,(H,13,15)
PubChem CID12311972
ChEMBLCHEMBL66949
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Relative potency0.0 -PMID2959777ChEMBL

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