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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucagon receptor
Species	Rattus norvegicus (Rat)
Gene	Gcgr
Synonym	GGR GL-R glucagon receptor GR
Disease	N/A for non-human GPCRs
Length	485
Amino acid sequence	MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
UniProt	P30082
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4720
IUPHAR	251
DrugBank	N/A

Ligand

Name	CHEMBL3325456
Molecular formula	C21H19N3O6
IUPAC name	N'-(4-hydroxy-3-nitrobenzoyl)-3-(4-propylphenyl)furan-2-carbohydrazide
Molecular weight	409.398
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	4.8
Synonyms	BDBM50057864 SCHEMBL3975712
Inchi Key	HIIHXFJANMZVSX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19N3O6/c1-2-3-13-4-6-14(7-5-13)16-10-11-30-19(16)21(27)23-22-20(26)15-8-9-18(25)17(12-15)24(28)29/h4-12,25H,2-3H2,1H3,(H,22,26)(H,23,27)
PubChem CID	11640146
ChEMBL	CHEMBL3325456
IUPHAR	N/A
BindingDB	50057864
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2900.0 nM	PMID25127101	BindingDB,ChEMBL

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