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GPCR

NameP2Y purinoceptor 1
SpeciesMeleagris gallopavo (Wild turkey)
GeneP2RY1
Synonym6H1 orphan receptor
ADP receptor
P2Y1
Purinergic receptor
DiseaseN/A for non-human GPCRs
Length362
Amino acid sequenceMTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProtP49652
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5720
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL3351026
Molecular formulaC18H19N6Na2O8PS2
IUPAC namedisodium;(2R,3R,4S,5R)-2-[6-amino-2-[2-(4-nitrophenyl)ethylsulfanyl]purin-9-yl]-5-(dioxidophosphinothioyloxymethyl)oxolane-3,4-diol
Molecular weight588.457
Hydrogen bond acceptor14
Hydrogen bond donor3
XlogPNone
SynonymsN/A
Inchi KeyHFXOOUIFEYBRMQ-CXKSGAPPSA-L
Inchi IDInChI=1S/C18H21N6O8PS2.2Na/c19-15-12-16(22-18(21-15)35-6-5-9-1-3-10(4-2-9)24(27)28)23(8-20-12)17-14(26)13(25)11(32-17)7-31-33(29,30)34;;/h1-4,8,11,13-14,17,25-26H,5-7H2,(H2,19,21,22)(H2,29,30,34);;/q;2*+1/p-2/t11-,13-,14-,17-;;/m1../s1
PubChem CID118719255
ChEMBLCHEMBL3351026
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.
Partition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
EC502360.0 nMPMID10479295ChEMBL

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