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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(3) dopamine receptor
Species	Homo sapiens (Human)
Gene	DRD3
Synonym	dopaminergic receptor D3 D3R D3 receptor dopamine D3 receptor
Disease	Unspecified Emesis; Gastric motility disorder Female sexual dysfunction Male sexual disorders Psychotic disorders Cocaine addiction Schizophrenia Drug abuse [ Show all ]
Length	400
Amino acid sequence	MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
UniProt	P35462
Protein Data Bank	3pbl
GPCR-HGmod model	P35462
3D structure model	This structure is from PDB ID 3pbl.
BioLiP	BL0191566, BL0191567
Therapeutic Target Database	T02551
ChEMBL	CHEMBL234
IUPHAR	216
DrugBank	BE0000581

Ligand

Name	HALOPERIDOL DECANOATE
Molecular formula	C31H41ClFNO3
IUPAC name	[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate
Molecular weight	530.121
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.9
Synonyms	C31H41ClFNO3 Decanoic acid, ester with 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone Halomonth KD 136 R 13762 SCHEMBL120575 AC1L1DVL CHEMBL1200986 EINECS 277-679-7 Haloperidol decanoate (JAN/USAN) KS-1419 ZINC8214574 API0024496 DECANOIC ACID 4-(4-CHLOROPHENYL)-1-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-4-PIPERIDINYL ESTER Haldol decanoas Haloperidol decanoate [USAN:USP:BAN:JAN] R 13,672 74050-97-8 CHEBI:31664 Depot haloperidol Halomonth (TN) KD 16 R-13,672 UNII-AC20PJ4101 AC20PJ4101 CTK5D9276 FT-0669103 Haloperidol Decanoate HCl LS-59345 [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate 4-(4-Chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidyl decanoate BDBM50053408 Decanoic acid, 4-(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester Haldol decanoate Haloperidol depot R 13672 77129-05-6 DTXSID50224951 KD-136 R-13672 W0040 AKOS025392169 D01898 Haldol Dec Haloperidol decanoate [USAN:BAN:JAN] MolPort-006-137-967 [ Show all ]
Inchi Key	GUTXTARXLVFHDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H41ClFNO3/c1-2-3-4-5-6-7-8-11-30(36)37-31(26-14-16-27(32)17-15-26)20-23-34(24-21-31)22-9-10-29(35)25-12-18-28(33)19-13-25/h12-19H,2-11,20-24H2,1H3
PubChem CID	52919
ChEMBL	CHEMBL1200986
IUPHAR	N/A
BindingDB	50053408
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3.5 nM	PMID25047579	BindingDB,ChEMBL

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