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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucagon receptor
Species	Rattus norvegicus (Rat)
Gene	Gcgr
Synonym	GGR GL-R glucagon receptor GR
Disease	N/A for non-human GPCRs
Length	485
Amino acid sequence	MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
UniProt	P30082
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4720
IUPHAR	251
DrugBank	N/A

Ligand

Name	CHEMBL3326187
Molecular formula	C22H21N3O6
IUPAC name	3-(4-butylphenyl)-N'-(4-hydroxy-3-nitrobenzoyl)furan-2-carbohydrazide
Molecular weight	423.425
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.3
Synonyms	SCHEMBL3975792 BDBM50057817 FDQHGPBWDBHZML-UHFFFAOYSA-N 3-(4-butylphenyl)-2-furancarboxylic acid 2-(4-hydroxy-3-nitrobenzoyl)hydrazide
Inchi Key	FDQHGPBWDBHZML-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21N3O6/c1-2-3-4-14-5-7-15(8-6-14)17-11-12-31-20(17)22(28)24-23-21(27)16-9-10-19(26)18(13-16)25(29)30/h5-13,26H,2-4H2,1H3,(H,23,27)(H,24,28)
PubChem CID	11633206
ChEMBL	CHEMBL3326187
IUPHAR	N/A
BindingDB	50057817
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	5500.0 nM	PMID25127101	BindingDB,ChEMBL

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