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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mas-related G-protein coupled receptor member X1
Species	Rattus norvegicus (Rat)
Gene	Mrgprx1
Synonym	Sensory neuron-specific G-protein coupled receptor 1
Disease	N/A for non-human GPCRs
Length	323
Amino acid sequence	MDPTISSLSTESTTLNKTGHPSCRPILTLSFLVPIITLLGLAGNTIVLWLLGFRMRRKAISVYVLNLSLADSFFLCCHFIDSLMRIMNFYGIYAHKLSKEILGNAAIIPYISGLSILSAISTERCLSVLWPIWYHCHRPRNMSAIICVLIWVLSFLMGILDWFFSGFLGETHHHLWKNVDFIVTAFLIFLFMLLFGSSLALLVRILCGSRRKPLSRLYVTISLTVMVYLICGLPLGLYLFLLYWFGIHLHYPFCHIYQVTVLLSCVNSSANPIIYFLVGSFRHRKKHRSLKMVLKRALEETPEEDEYTDSHVQKPTEISERRC
UniProt	Q8R4G1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3341575
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Rfamide
Molecular formula	C15H24N6O2
IUPAC name	(2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight	320.397
Hydrogen bond acceptor	4
Hydrogen bond donor	5
XlogP	-2.0
Synonyms	119051-99-9 H-Arg-Phe-NH2 AC1Q5IPT R-F-NH2 (2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide ZINC2554967 34388-59-5 L-Phenylalaninamide, L-arginyl- Arg-phe-NH2 (S)-2-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide CHEMBL3343990 AC1L3U57 n5-(diaminomethylidene)-l-ornithyl-l-phenylalaninamide arginylphenylalaninamide SCHEMBL1373212 [ Show all ]
Inchi Key	CQZWLVDDIOZTJI-RYUDHWBXSA-N
Inchi ID	InChI=1S/C15H24N6O2/c16-11(7-4-8-20-15(18)19)14(23)21-12(13(17)22)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H2,17,22)(H,21,23)(H4,18,19,20)/t11-,12-/m0/s1
PubChem CID	122185
ChEMBL	CHEMBL3343990
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	6309.57 nM	PMID25288495	ChEMBL

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