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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd2
Synonym	D2 receptor D2(415) and D₂₍₄₄₄₎ D2A and D_2B D2R Dopamine D2 receptor dopamine receptor 2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
UniProt	P61169
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL339
IUPHAR	215
DrugBank	N/A

Ligand

Name	76149-15-0
Molecular formula	C16H24N2
IUPAC name	N-[2-(1H-indol-4-yl)ethyl]-N-propylpropan-1-amine
Molecular weight	244.382
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	4.1
Synonyms	4-[2-(dipropylamino)ethyl]indole DPAI N-[2-(1H-indol-4-yl)ethyl]-N-propylpropan-1-amine AC1Q2XQB 4-(2-[di-n-propylamino]ethyl)indole CHEMBL67040 DTXSID10227004 SCHEMBL11177660 1H-Indole-4-ethanamine, N,N-dipropyl- AFRBPRLOPBAGCM-UHFFFAOYSA-N 4-Dpaei Desoxo-2-ene Ropinirole N,N-Dipropyl-1H-indole-4-(ethanamine) AC1MJ5HP ZINC26260001 4-(2-Di-N-propylaminoethyl)indole [ Show all ]
Inchi Key	AFRBPRLOPBAGCM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H24N2/c1-3-11-18(12-4-2)13-9-14-6-5-7-16-15(14)8-10-17-16/h5-8,10,17H,3-4,9,11-13H2,1-2H3
PubChem CID	3086054
ChEMBL	CHEMBL67040
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Change	-69.0 %	PMID2570151	ChEMBL
PRL	5.0 ng ml-1	PMID2570151	ChEMBL

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