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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide FF receptor 2
Species	Rattus norvegicus (Rat)
Gene	Npffr2
Synonym	F8Famide receptor G protein-coupled receptor 74 G-protein coupled receptor 74 GPR74 Neuropeptide G-protein coupled receptor NPFF2 receptor NPGPR [ Show all ]
Disease	N/A for non-human GPCRs
Length	417
Amino acid sequence	MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
UniProt	Q9EQD2
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3425
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2181307
Molecular formula	C21H35N7O3
IUPAC name	(2S)-2-amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Molecular weight	433.557
Hydrogen bond acceptor	5
Hydrogen bond donor	6
XlogP	-0.1
Synonyms	N/A
Inchi Key	ZVGJPQMEEYQNAU-ULQDDVLXSA-N
Inchi ID	InChI=1S/C21H35N7O3/c1-13(2)11-15(22)19(30)27-16(9-6-10-26-21(24)25)20(31)28-17(18(23)29)12-14-7-4-3-5-8-14/h3-5,7-8,13,15-17H,6,9-12,22H2,1-2H3,(H2,23,29)(H,27,30)(H,28,31)(H4,24,25,26)/t15-,16-,17-/m0/s1
PubChem CID	71453914
ChEMBL	CHEMBL2181307
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	45.0 %	PMID22909119	ChEMBL
Inhibition	49.0 %	PMID22909119	ChEMBL
Inhibition	59.0 %	PMID22909119	ChEMBL

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