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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Bos taurus (Bovine)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
UniProt	P28190
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4975
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL178863
Molecular formula	C15H14N4O5
IUPAC name	diethyl 4-oxo-[1,2,4]triazolo[1,5-a]quinoxaline-2,5-dicarboxylate
Molecular weight	330.3
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.2
Synonyms	BDBM50178645 diethyl 4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2,5-dicarboxylate
Inchi Key	CJMOFNWHVBBDDW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H14N4O5/c1-3-23-14(21)11-16-12-13(20)18(15(22)24-4-2)9-7-5-6-8-10(9)19(12)17-11/h5-8H,3-4H2,1-2H3
PubChem CID	11493648
ChEMBL	CHEMBL178863
IUPHAR	N/A
BindingDB	50178645
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	14.0 %	PMID16335918	ChEMBL

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