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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin F2-alpha receptor
Species	Mus musculus (Mouse)
Gene	Ptgfr
Synonym	prostaglandin F2-alpha receptor prostaglandin F receptor (FP) prostaglandin F receptor PGF2-alpha receptor PGF2 alpha receptor PGF receptor PF2AR FP receptor Prostanoid FP receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	366
Amino acid sequence	MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
UniProt	P43117
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5000
IUPHAR	344
DrugBank	N/A

Ligand

Name	CHEMBL3245757
Molecular formula	C16H20O4
IUPAC name	3-(6-propyl-5,7-dihydrocyclopenta[f][1,3]benzodioxol-6-yl)propanoic acid
Molecular weight	276.332
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	ZINC169321906
Inchi Key	YUUHQQFHLXECRK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H20O4/c1-2-4-16(5-3-15(17)18)8-11-6-13-14(20-10-19-13)7-12(11)9-16/h6-7H,2-5,8-10H2,1H3,(H,17,18)
PubChem CID	90672308
ChEMBL	CHEMBL3245757
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	20.0 %	PMID423186	ChEMBL

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