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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd1
Synonym	D1 receptor D1A DADR dopamine D1 receptor Dopamine-1A receptor Gpcr15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProt	P18901
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL265
IUPHAR	214
DrugBank	N/A

Ligand

Name	CHEMBL17231
Molecular formula	C15H22N2O2S
IUPAC name	7-[2-(dipropylamino)ethyl]-4-hydroxy-3H-1,3-benzothiazol-2-one
Molecular weight	294.413
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.4
Synonyms	7-(2-Dipropylamino-ethyl)-4-hydroxy-3H-benzothiazol-2-one 4-Hydroxy-7-[2-(dipropylamino)ethyl]benzothiazole-2(3H)-one BDBM50020682 SCHEMBL10750554
Inchi Key	CFSNGNNMGHLIPH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H22N2O2S/c1-3-8-17(9-4-2)10-7-11-5-6-12(18)13-14(11)20-15(19)16-13/h5-6,18H,3-4,7-10H2,1-2H3,(H,16,19)
PubChem CID	13506603
ChEMBL	CHEMBL17231
IUPHAR	N/A
BindingDB	50020682
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
K bind	516.0 nM	PMID2955118	ChEMBL

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