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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 2
Species	Rattus norvegicus (Rat)
Gene	Cnr2
Synonym	Peripheral cannabinoid receptor CB2-R CB2 receptor CB2 CB-2 cannabinoid receptor 2 (spleen) cannabinoid receptor 2 (macrophage) rCB2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	360
Amino acid sequence	MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
UniProt	Q9QZN9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2470
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2316289
Molecular formula	C19H28N4O3
IUPAC name	N-cyclohexyl-7-(2-ethoxyethyl)-1,3-dimethyl-4-oxopyrazolo[3,4-b]pyridine-5-carboxamide
Molecular weight	360.458
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	BDBM50426116
Inchi Key	CFPCMFLPKKZGMJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H28N4O3/c1-4-26-11-10-23-12-15(18(25)20-14-8-6-5-7-9-14)17(24)16-13(2)21-22(3)19(16)23/h12,14H,4-11H2,1-3H3,(H,20,25)
PubChem CID	71562646
ChEMBL	CHEMBL2316289
IUPHAR	N/A
BindingDB	50426116
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	1.0 %	PMID23350768	ChEMBL
Ki	<10000.0 nM	PMID23350768	BindingDB,ChEMBL

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