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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor DM1
Species	Drosophila melanogaster (Fruit fly)
Gene	mAChR-A
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	805
Amino acid sequence	MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN
UniProt	P16395
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2366467
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	4-Damp methiodide
Molecular formula	C21H26INO2
IUPAC name	(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate;iodide
Molecular weight	451.348
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	None
Synonyms	1952-15-4 4-diphenylacetoxy-1,1-dimethylpiperidinium iodide B6317 CHEMBL76897 J-012645 NCGC00261092-01 Tox21_500407 4-DAMP 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium iodide C21H26NO2.I FT-0742369 MFCD00078564 SCHEMBL3987354 1,1-dimethyl-4-diphenylacetoxypiperidinium iodide 4-DAMP methyliodide AC1MHZ3P CHEBI:73340 HMS3266E10 N,N-dimethyl-4-(diphenylacetoxy)piperidinium iodide SR-01000075326-1 4-((Diphenylacetyl)oxy)-1,1-dimethylpiperidinium iodide 4-DIPHENYLACETOXY-N-METHYL-PIPERIDINE METHIODIDE BN0026 D-104 LP00407 Piperidinium, 4-((diphenylacetyl)oxy)-1,1-dimethyl-, iodide 4-DAMP iodide 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-piperidinium iodide CCG-221711 HMS2234J07 MLS000859984 SMR000326843 1,1-dimethyl-4-diphenylacetoxypiperidiniumiodide 4-DAMP, >=98% (HPLC) AKOS024458363 HMS3369K06 NCGC00093833-01 SR-01000075326-3 4-(2,2-diphenylacetoxy)-1,1-dimethylpiperidinium iodide 4-Diphenylacetoxy-N-methylpiperidine methiodide C-56134 EU-0100407 LS-173781 REGID_for_CID_3014059 81405-11-0 (Parent) CCG-222526 HMS3261A16 MolPort-003-940-940 SR-01000075326 (1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate iodide [ Show all ]
Inchi Key	WWJHRSCUAQPFQO-UHFFFAOYSA-M
Inchi ID	InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
PubChem CID	3014059
ChEMBL	CHEMBL76897
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	15.0 nM	PMID17319687	ChEMBL
Ki	18.0 nM	PMID17319687	ChEMBL

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