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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin D2 receptor
Species	Rattus norvegicus (Rat)
Gene	Ptgdr
Synonym	DP1 receptor PGD receptor PGD2 receptor DP1 prostaglandin D2 receptor (DP) Prostanoid DP receptor prostanoid DP receptor-like PTGDR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MNESYRCQAATWVERGSSATMGGVAFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSLAFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMCSLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKTFTRPLIYRNWCSHSWQTNMESTL
UniProt	Q9R261
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	338
DrugBank	N/A

Ligand

Name	Prostaglandin D2 methyl ester
Molecular formula	C21H34O5
IUPAC name	methyl 7-[5-hydroxy-2-(3-hydroxyoct-1-enyl)-3-oxocyclopentyl]hept-5-enoate
Molecular weight	366.498
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.9
Synonyms	AC1N6QW1 49852-81-5 methyl 7-[5-hydroxy-2-(3-hydroxyoct-1-enyl)-3-oxocyclopentyl]hept-5-enoate
Inchi Key	WNBMQMMGBBWUOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H34O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-19,22-23H,3-4,6-7,9-12,15H2,1-2H3
PubChem CID	4264392
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82214
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	27.0 nM	PMID6292197	BindingDB

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