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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Mus musculus (Mouse)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
UniProt	P30557
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4336
IUPHAR	342
DrugBank	N/A

Ligand

Name	CHEMBL1813119
Molecular formula	C29H28N2O6
IUPAC name	2-[5-methoxy-2-methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-3-yl]acetic acid
Molecular weight	500.551
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50350370 SCHEMBL5644909
Inchi Key	WMUFBYGHMKJROO-QFIPXVFZSA-N
Inchi ID	InChI=1S/C29H28N2O6/c1-18-23(15-28(32)33)24-14-21(35-3)12-13-25(24)31(18)29(34)19-8-10-20(11-9-19)36-17-22-16-30(2)26-6-4-5-7-27(26)37-22/h4-14,22H,15-17H2,1-3H3,(H,32,33)/t22-/m0/s1
PubChem CID	10185382
ChEMBL	CHEMBL1813119
IUPHAR	N/A
BindingDB	50350370
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2500.0 nM	PMID21737285	BindingDB,ChEMBL

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