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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Canis lupus familiaris (Dog)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	Q9GJU1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2703
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL417148
Molecular formula	C19H25ClN4O2
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(pyridin-2-ylmethoxy)benzamide
Molecular weight	376.885
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.1
Synonyms	BDBM50023832 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(pyridin-2-ylmethoxy)-benzamide
Inchi Key	WJXMHSPYDSGKRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25ClN4O2/c1-3-24(4-2)10-9-23-19(25)15-11-16(20)17(21)12-18(15)26-13-14-7-5-6-8-22-14/h5-8,11-12H,3-4,9-10,13,21H2,1-2H3,(H,23,25)
PubChem CID	14116928
ChEMBL	CHEMBL417148
IUPHAR	N/A
BindingDB	50023832
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	<3.0 mg.kg-1	PMID3397992	ChEMBL

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