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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd2
Synonym	D2 receptor D2(415) and D₂₍₄₄₄₎ D2A and D_2B D2R Dopamine D2 receptor dopamine receptor 2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
UniProt	P61169
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL339
IUPHAR	215
DrugBank	N/A

Ligand

Name	CHEMBL1173017
Molecular formula	C29H39N5
IUPAC name	4-[4-[6-(4-phenylpiperazin-1-yl)hexyl]piperazin-1-yl]quinoline
Molecular weight	457.666
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50322370 SCHEMBL4527749 4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-yl)quinoline
Inchi Key	AEQHEVDDTLOOMD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2
PubChem CID	11539823
ChEMBL	CHEMBL1173017
IUPHAR	N/A
BindingDB	50322370
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	41.0 nM	PMID20481570	BindingDB,ChEMBL

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