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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H2 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH2
Synonym	Gastric receptor I H2R HH2R
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSLAVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNEVYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYHQLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
UniProt	P47747
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2882
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3220892
Molecular formula	C17H23N5O
IUPAC name	N-[N'-(3-imidazol-1-ylpropyl)carbamimidoyl]-3-phenylbutanamide
Molecular weight	313.405
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.7
Synonyms	N/A
Inchi Key	AEOZDVJZTYYDHL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H23N5O/c1-14(15-6-3-2-4-7-15)12-16(23)21-17(18)20-8-5-10-22-11-9-19-13-22/h2-4,6-7,9,11,13-14H,5,8,10,12H2,1H3,(H3,18,20,21,23)
PubChem CID	90667434
ChEMBL	CHEMBL3220892
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Emax	0.69 %	MedChemComm, (2014) 5:1:72	ChEMBL
Kd	<31622.8 nM	MedChemComm, (2014) 5:1:72	ChEMBL
pD2	4.16 -	MedChemComm, (2014) 5:1:72	ChEMBL

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