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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Bos taurus (Bovine)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
UniProt	P28190
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4975
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL159195
Molecular formula	C19H18N6
IUPAC name	N-(3-methylphenyl)-3-(2-phenylethyl)triazolo[4,5-d]pyrimidin-7-amine
Molecular weight	330.395
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50063193 (3-Phenethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-m-tolyl-amine
Inchi Key	BZKYXXHXXFNVIV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18N6/c1-14-6-5-9-16(12-14)22-18-17-19(21-13-20-18)25(24-23-17)11-10-15-7-3-2-4-8-15/h2-9,12-13H,10-11H2,1H3,(H,20,21,22)
PubChem CID	10640176
ChEMBL	CHEMBL159195
IUPHAR	N/A
BindingDB	50063193
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4380.0 nM	PMID9513594	BindingDB,ChEMBL

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