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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1D
Species	Cavia porcellus (Guinea pig)
Gene	HTR1D
Synonym	5-HT-1D 5-HT1D Serotonin receptor 1D
Disease	N/A for non-human GPCRs
Length	376
Amino acid sequence	MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFTTAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATKTLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEDFRQAFQKVVHFRKAS
UniProt	Q60484
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304407
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL70355
Molecular formula	C27H32N2O3
IUPAC name	3-[3-(dimethylamino)propyl]-N-[4-[4-(hydroxymethyl)-2-methylphenyl]phenyl]-4-methoxybenzamide
Molecular weight	432.564
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.5
Synonyms	VNMPDHQLXRNAMA-UHFFFAOYSA-N 3-(Dimethylaminopropyl]-N-[4'-(1-hydroxymethyl)-2'-methyl[1,1'-biphenyl]-4-yl]-4-methoxybenzamide 3-[3-(Dimethylamino)propyl]-4-methoxy-N-[2'-methyl-4'-(hydroxymethyl)-1,1'-biphenyl-4-yl]benzamide SCHEMBL6497266
Inchi Key	VNMPDHQLXRNAMA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32N2O3/c1-19-16-20(18-30)7-13-25(19)21-8-11-24(12-9-21)28-27(31)23-10-14-26(32-4)22(17-23)6-5-15-29(2)3/h7-14,16-17,30H,5-6,15,18H2,1-4H3,(H,28,31)
PubChem CID	10002935
ChEMBL	CHEMBL70355
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	45.0 mg.kg-1	PMID8057272	ChEMBL
Inhibition	52.0 %	PMID8057272	ChEMBL

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