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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cholecystokinin receptor type A
Species	Cavia porcellus (Guinea pig)
Gene	CCKAR
Synonym	CCK-A receptor CCK-AR CCK1-R Cholecystokinin-1 receptor
Disease	N/A for non-human GPCRs
Length	430
Amino acid sequence	MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
UniProt	Q63931
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3501
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL112682
Molecular formula	C31H38N4O4
IUPAC name	N-[(2R)-1-(dipentylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-8-hydroxy-4-oxo-1H-quinoline-2-carboxamide
Molecular weight	530.669
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	5.9
Synonyms	(R)-2-(4,8-Dihydroxy-2-quinolinylcarbonylamino)-3-(1H-indol-3-yl)-N,N-dipentylpropanamide BDBM50008627 (R)-4,8-Dihydroxy-quinoline-2-carboxylic acid [1-dipentylcarbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Inchi Key	BYIBEZIVVZSAAH-AREMUKBSSA-N
Inchi ID	InChI=1S/C31H38N4O4/c1-3-5-9-16-35(17-10-6-4-2)31(39)26(18-21-20-32-24-14-8-7-12-22(21)24)34-30(38)25-19-28(37)23-13-11-15-27(36)29(23)33-25/h7-8,11-15,19-20,26,32,36H,3-6,9-10,16-18H2,1-2H3,(H,33,37)(H,34,38)/t26-/m1/s1
PubChem CID	9914964
ChEMBL	CHEMBL112682
IUPHAR	N/A
BindingDB	50008627
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	21.0 nM	PMID1766000	BindingDB,ChEMBL

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