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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	2-oxoglutarate receptor 1
Species	Rattus norvegicus (Rat)
Gene	Oxgr1
Synonym	P2Y purinoceptor 15 P2RY15 oxoglutarate receptor GPR99 GPR80 G-protein coupled receptor 80 G protein-coupled receptor 99 G protein-coupled receptor 80 Alpha-ketoglutarate receptor 1 2-oxoglutarate receptor 1 P2Y15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	337
Amino acid sequence	MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
UniProt	Q6Y1R5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2325
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	BRN 0591237
Molecular formula	C17H18N6O4
IUPAC name	(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-benzyl-3,4-dihydroxyoxolane-2-carboxamide
Molecular weight	370.369
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	0.4
Synonyms	1-(6-Amino-9H-purin-9-yl)-N-benzyl-1-deoxyribofuranuronamide DTXSID00206585 AC1MII33 (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-benzyl-3,4-dihydroxyoxolane-2-carboxamide BDBM85777 57872-79-4 LS-143750 Adenosine-5'-(N-benzyl)carboxamide 1-(6-Amino-9H-purin-9-yl)-N-benzyl-1-deoxy-beta-D-ribofuranuronamide Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-N-benzyl-1-deoxy- B-NECA [ Show all ]
Inchi Key	VDAITUUOENAMKK-PFHKOEEOSA-N
Inchi ID	InChI=1S/C17H18N6O4/c18-14-10-15(21-7-20-14)23(8-22-10)17-12(25)11(24)13(27-17)16(26)19-6-9-4-2-1-3-5-9/h1-5,7-8,11-13,17,24-25H,6H2,(H,19,26)(H2,18,20,21)/t11-,12+,13-,17+/m0/s1
PubChem CID	3044932
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85777
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	42.0 nM	PMID11170630	BindingDB

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