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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 4
Species	Rattus norvegicus (Rat)
Gene	Sstr4
Synonym	SRIF2B SS-4-R SS4-R SS4R SST4 receptor
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MNTPATLPLGGEDTTWTPGINASWAPDEEEDAVRSDGTGTAGMVTIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPAWSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRSFQRVLCLRCCLLETTGGAEEEPLDYYATALKSRGGPGCICPPLPCQQEPMQAEPACKRVPFTKTTTF
UniProt	P30937
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	358
DrugBank	N/A

Ligand

Name	CHEMBL3350185
Molecular formula	C62H76N12O12
IUPAC name	(2S)-6-amino-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide
Molecular weight	1181.36
Hydrogen bond acceptor	14
Hydrogen bond donor	13
XlogP	4.5
Synonyms	BIM 23066 BIM-23066 BDBM85008
Inchi Key	UULQBXHJYAJQGW-WMJDRJGJSA-N
Inchi ID	InChI=1S/C62H76N12O12/c1-36(2)53(62(84)71-51(31-39-16-8-5-9-17-39)61(83)73-54(37(3)75)55(65)77)72-57(79)48(20-12-13-29-63)67-60(82)52(34-42-35-66-47-19-11-10-18-45(42)47)70-59(81)50(33-41-23-27-44(76)28-24-41)69-58(80)49(32-40-21-25-43(26-22-40)74(85)86)68-56(78)46(64)30-38-14-6-4-7-15-38/h4-11,14-19,21-28,35-37,46,48-54,66,75-76H,12-13,20,29-34,63-64H2,1-3H3,(H2,65,77)(H,67,82)(H,68,78)(H,69,80)(H,70,81)(H,71,84)(H,72,79)(H,73,83)/t37-,46-,48+,49+,50+,51+,52-,53+,54+/m1/s1
PubChem CID	16209188
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85008
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2.4 nM	PMID8102785	BindingDB

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