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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Pyroglutamylated RF-amide peptide receptor
Species	Rattus norvegicus (Rat)
Gene	Qrfpr
Synonym	AQ27 QRFP receptor peptide p518 receptor Orexigenic neuropeptide QRFP receptor GPR103 G-protein coupled receptor 103 G protein-coupled receptor 103 SP9155 [ Show all ]
Disease	N/A for non-human GPCRs
Length	433
Amino acid sequence	MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKVAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHICCLEEWASPVHQRIYSTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVIMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVKESSSPARKPGNSGISMMQKRAKLSRPQRPVEETKGDTFSDASIDVKLCEQPREKRQLKRQLAFFSSELSENSTFGSGHEL
UniProt	P83858
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1949484
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	az599
Molecular formula	C25H35N3O4S
IUPAC name	[5-ethylsulfonyl-2-(oxan-4-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-8-yl]-(4-methylpiperidin-1-yl)methanone
Molecular weight	473.632
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.1
Synonyms	CHEMBL1950351 ZINC43206729 BDBM50364920 KB-270804 910798-82-2 SCHEMBL3310279 [ Show all ]
Inchi Key	UCMNIYFDRVBMFV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H35N3O4S/c1-3-33(30,31)28-23-5-4-19(25(29)26-11-6-18(2)7-12-26)16-21(23)22-17-27(13-8-24(22)28)20-9-14-32-15-10-20/h4-5,16,18,20H,3,6-15,17H2,1-2H3
PubChem CID	24894028
ChEMBL	CHEMBL1950351
IUPHAR	N/A
BindingDB	50364920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	>50.0 %	PMID22284817	ChEMBL

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