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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Mus musculus (Mouse)
Gene	Drd1
Synonym	D1 receptor D1A DADR Dopamine D1 receptor Dopamine-1A receptor Gpcr15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDAEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProt	Q61616
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3071
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL138809
Molecular formula	C20H23NO2
IUPAC name	1'-benzyl-1-methoxyspiro[1H-2-benzofuran-3,4'-piperidine]
Molecular weight	309.409
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.0
Synonyms	1''-benzyl-3-methoxy-3H-spiro[2-benzofuran-1,4''-piperidine] 1'-benzyl-3-methoxy-3h-spiro[[2]benzofuran-1,4'-piperidine] BDBM50108659 1''-benzyl-3-methoxy-3H-spiro[isobenzofuran-1,4''-piperidine] 1'-Benzyl-3-methoxyspiro[isobenzofuran-1(3H),4'-piperidine] 1''-benzyl-3-methoxyspiro[1,3-dihydroisobenzofuran-1,4''-(hexahydropyridine)] [ Show all ]
Inchi Key	RZZAEVQHACUOGI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23NO2/c1-22-19-17-9-5-6-10-18(17)20(23-19)11-13-21(14-12-20)15-16-7-3-2-4-8-16/h2-10,19H,11-15H2,1H3
PubChem CID	10357986
ChEMBL	CHEMBL138809
IUPHAR	N/A
BindingDB	50108659
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<10000.0 nM	PMID11784148	BindingDB,ChEMBL

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