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Name | G-protein coupled receptor 35 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Gpr35 |
Synonym | G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor |
Disease | N/A for non-human GPCRs |
Length | 307 |
Amino acid sequence | MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT |
UniProt | Q9ES90 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2390813 |
IUPHAR | 102 |
DrugBank | N/A |
Name | CHEMBL2392163 |
---|---|
Molecular formula | C20H16FNO6 |
IUPAC name | ethyl 6-fluoro-8-[(4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylate |
Molecular weight | 385.347 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 1 |
XlogP | 2.9 |
Synonyms | BDBM50436029 4-Oxo-6-fluoro-8-(4-methoxybenzoylamino)-2-chromene-2-carboxylic acid ethyl ester |
Inchi Key | RZJVSJYNTZDPDF-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H16FNO6/c1-3-27-20(25)17-10-16(23)14-8-12(21)9-15(18(14)28-17)22-19(24)11-4-6-13(26-2)7-5-11/h4-10H,3H2,1-2H3,(H,22,24) |
PubChem CID | 71734940 |
ChEMBL | CHEMBL2392163 |
IUPHAR | N/A |
BindingDB | 50436029 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 7.0 % | PMID23713606 | ChEMBL |
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