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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Gastrin/cholecystokinin type B receptor
Species	Rattus norvegicus (Rat)
Gene	Cckbr
Synonym	CHOLREC Cholecystokinin-2 receptor CCK2-R CCK2 receptor CCK-BR CCK-B/gastrin receptor CCK-B receptor gastrin/cholecystokinin type B receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCVQLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTWRAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPQPLPDEDPPTPSIASLSRLSYTTISTLGPG
UniProt	P30553
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3508
IUPHAR	77
DrugBank	N/A

Ligand

Name	CHEMBL100103
Molecular formula	C24H30N2O
IUPAC name	2-[5-methyl-2-(4-methylphenyl)-1H-indol-3-yl]-N,N-dipropylacetamide
Molecular weight	362.517
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50045870 N,N-Dipropyl-2-(4-methylphenyl)-5-methyl-1H-indole-3-acetamide 2-(5-Methyl-2-p-tolyl-1H-indol-3-yl)-N,N-dipropyl-acetamide
Inchi Key	BQTZSYWEYWBRNP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H30N2O/c1-5-13-26(14-6-2)23(27)16-21-20-15-18(4)9-12-22(20)25-24(21)19-10-7-17(3)8-11-19/h7-12,15,25H,5-6,13-14,16H2,1-4H3
PubChem CID	10067228
ChEMBL	CHEMBL100103
IUPHAR	N/A
BindingDB	50045870
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1000.0 nM	PMID8411007	BindingDB,ChEMBL

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