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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Canis lupus familiaris (Dog)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	Q9GJU1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2703
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL39623
Molecular formula	C20H26ClN3O2
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-phenylmethoxybenzamide
Molecular weight	375.897
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.1
Synonyms	AC1Q3QFW 4-Amino-2-benzyloxy-5-chloro-N-(2-diethylamino-ethyl)-benzamide N-(Diethylaminoethyl)-2-benzyloxy-4-amino-5-chlorobenzamide 23205-22-3 BDBM50023805 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-(phenylmethoxy)benzamide AC1L4QW4 4-amino-2-(benzyloxy)-5-chloro-n-[2-(diethylamino)ethyl]benzamide Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-(phenylmethoxy)- 4-amino-5-chloro-N-(2-diethylaminoethyl)-2-phenylmethoxybenzamide LS-25422 [ Show all ]
Inchi Key	RNDGARWUQSIOQW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H26ClN3O2/c1-3-24(4-2)11-10-23-20(25)16-12-17(21)18(22)13-19(16)26-14-15-8-6-5-7-9-15/h5-9,12-13H,3-4,10-11,14,22H2,1-2H3,(H,23,25)
PubChem CID	211484
ChEMBL	CHEMBL39623
IUPHAR	N/A
BindingDB	50023805
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	<1.0 mg.kg-1	PMID3397992	ChEMBL

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