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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H3 receptor
Species	Rattus norvegicus (Rat)
Gene	Hrh3
Synonym	GPCR97 H3 receptor H3R HH3R
Disease	N/A for non-human GPCRs
Length	445
Amino acid sequence	MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
UniProt	Q9QYN8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4124
IUPHAR	264
DrugBank	N/A

Ligand

Name	CID 44370594
Molecular formula	C14H21N3O6
IUPAC name	(E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-propan-2-ylcarbamate
Molecular weight	327.337
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	None
Synonyms	N/A
Inchi Key	ADQANUWWTHCQCN-WLHGVMLRSA-N
Inchi ID	InChI=1S/C10H17N3O2.C4H4O4/c1-8(2)13-10(14)15-5-3-4-9-6-11-7-12-9;5-3(6)1-2-4(7)8/h6-8H,3-5H2,1-2H3,(H,11,12)(H,13,14);1-2H,(H,5,6)(H,7,8)/b;2-1+
PubChem CID	44370594
ChEMBL	CHEMBL350456
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	79.43 nM	PMID10052966	ChEMBL
Ki	82.0 nM	PMID10052966	ChEMBL

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