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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Cavia porcellus (Guinea pig)
Gene	Adrb2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
UniProt	Q8K4Z4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5414
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Colterol
Molecular formula	C12H19NO3
IUPAC name	4-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,2-diol
Molecular weight	225.288
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	-0.4
Synonyms	18866-78-9 BDBM50421728 Colterolum [INN-Latin] S 1541 (+-)-tert-Butyl noradrenaline 4363-02-4 dl-N-tert-Butylnorepinephrine Win 5563 1,2-Benzenediol, 4-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-,(+-)- AC1L18FI Colterol [INN] N-t-Butylarterenol (+-)-N-t-Butylnoradrenaline 4-(2-((1-Dimethylethyl)amino)-1-hydroxyethyl)-1,2-benzenediol Benzyl alcohol, alpha-((tert-butylamino)methyl)-3,4-dihydroxy-, (+-)- CTK1C8071 SCHEMBL249585 (+/-)-N-tert-butylarterenol CHEMBL1159715 FT-0716336 1,2-Benzenediol, 4-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]- ACM18866789 Colterolum N-tert-butyl-2-(3,4-dihydroxyphenyl)-2-hydroxyethylamine (+-)-N-tert-Butylarterenol 4-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,2-diol CHEBI:73085 dl-1-(3,4-Dihydroxyphenyl)-2-tert-butylaminoethanol t-Butylnorepinephrine 1,2-Benzenediol, 4-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- a-[(t-butylamino)methyl]-3,4-dihydroxy-benzyl alcohol KWD 2026 [ Show all ]
Inchi Key	PHSMOUBHYUFTDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-5-9(14)10(15)6-8/h4-6,11,13-16H,7H2,1-3H3
PubChem CID	25104
ChEMBL	CHEMBL1159715
IUPHAR	N/A
BindingDB	50421728
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	1.3 nM	PMID20504	ChEMBL
Intrinsic activity	1.0 -	PMID20504	ChEMBL

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