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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL631592
Molecular formula	C12H13F2N3
IUPAC name	N-ethyl-3,4-difluoro-N-(1H-imidazol-5-ylmethyl)aniline
Molecular weight	237.254
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.3
Synonyms	CHEMBL3645389 (3,4-difluoro-phenyl)-ethyl-(3h-imidazol-4-ylmethyl)-amine BDBM106594 1020815-00-2 US8586617, 58
Inchi Key	BKPYZFRTPMOBCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H13F2N3/c1-2-17(7-9-6-15-8-16-9)10-3-4-11(13)12(14)5-10/h3-6,8H,2,7H2,1H3,(H,15,16)
PubChem CID	24947147
ChEMBL	CHEMBL3645389
IUPHAR	N/A
BindingDB	106594
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.4 nM	, None	BindingDB,ChEMBL

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