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Name | Muscarinic acetylcholine receptor M3 |
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Species | Mus musculus (Mouse) |
Gene | Chrm3 |
Synonym | cholinergic receptor, muscarinic 3 cholinergic receptor, muscarinic 3, cardiac Chrm-3 cholinergic receptor M3 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 589 |
Amino acid sequence | MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVSQLDSYNISQTSGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGTKRSSRRKYGGCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPDKDLGTMDVERNAHKLQAQKSMDDRDNCQKDFSKLPIQLESAVDTAKTSDTNSSVDKTTAALPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL |
UniProt | Q9ERZ3 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5105 |
IUPHAR | N/A |
DrugBank | N/A |
Name | methyl 6-amino-2,3,4,5-tetrahydropyridine-3-carboxylate hydrochloride |
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Molecular formula | C7H13ClN2O2 |
IUPAC name | methyl 6-amino-2,3,4,5-tetrahydropyridine-3-carboxylate;hydrochloride |
Molecular weight | 192.643 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 2 |
XlogP | None |
Synonyms | MolPort-039-242-762 Z2418193676 146422-38-0 CHEMBL553602 PESXKMCPNBSHGM-UHFFFAOYSA-N [ Show all ] |
Inchi Key | PESXKMCPNBSHGM-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C7H12N2O2.ClH/c1-11-7(10)5-2-3-6(8)9-4-5;/h5H,2-4H2,1H3,(H2,8,9);1H |
PubChem CID | 45259453 |
ChEMBL | CHEMBL553602 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 14000.0 nM | PMID9111297 | ChEMBL |
Smax | 140.0 % | PMID9111297 | ChEMBL |
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