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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP4 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger4
Synonym	EP2 EP4 receptor PGE receptor EP4 subtype PGE2 receptor EP4 subtype Prostanoid EP4 receptor
Disease	N/A for non-human GPCRs
Length	488
Amino acid sequence	MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVACRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDGSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSETLKLSEKCI
UniProt	P43114
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4086
IUPHAR	343
DrugBank	N/A

Ligand

Name	CHEMBL562411
Molecular formula	C21H35NO5S
IUPAC name	7-[[4-(1-hydroxyhexyl)phenyl]methyl-methylsulfonylamino]heptanoic acid
Molecular weight	413.573
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.6
Synonyms	BDBM50293498 PEGKTVODCSBWQI-UHFFFAOYSA-N 7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)heptanoic acid SCHEMBL1471097 7-{[4-(1-hydroxy-hexyl)-benzyl]-methanesulfonyl-amino}-heptanoic acid
Inchi Key	PEGKTVODCSBWQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H35NO5S/c1-3-4-7-10-20(23)19-14-12-18(13-15-19)17-22(28(2,26)27)16-9-6-5-8-11-21(24)25/h12-15,20,23H,3-11,16-17H2,1-2H3,(H,24,25)
PubChem CID	10223499
ChEMBL	CHEMBL562411
IUPHAR	N/A
BindingDB	50293498
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<3200.0 nM	PMID19250823	BindingDB,ChEMBL

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