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Name | G-protein coupled receptor 35 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Gpr35 |
Synonym | G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor |
Disease | N/A for non-human GPCRs |
Length | 307 |
Amino acid sequence | MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT |
UniProt | Q9ES90 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2390813 |
IUPHAR | 102 |
DrugBank | N/A |
Name | CHEMBL2392145 |
---|---|
Molecular formula | C12H9NO5 |
IUPAC name | 8-acetamido-4-oxochromene-2-carboxylic acid |
Molecular weight | 247.206 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 2 |
XlogP | 0.5 |
Synonyms | 8-acetamido-4-oxo-4H-chromene-2-carboxylic acid 1443366-92-4 BDBM50436036 |
Inchi Key | OZSBJMMDIFFFMS-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C12H9NO5/c1-6(14)13-8-4-2-3-7-9(15)5-10(12(16)17)18-11(7)8/h2-5H,1H3,(H,13,14)(H,16,17) |
PubChem CID | 71734941 |
ChEMBL | CHEMBL2392145 |
IUPHAR | N/A |
BindingDB | 50436036 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 3.0 % | PMID23713606 | ChEMBL |
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