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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H4 receptor
Species	Rattus norvegicus (Rat)
Gene	Hrh4
Synonym	GPCR105 H4 receptor H4R HH4R
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MSESNGTDVLPLTAQVPLAFLMSLLAFAITIGNAVVILAFVADRNLRHRSNYFFLNLAISDFFVGVISIPLYIPHTLFNWNFGSGICMFWLITDYLLCTASVYSIVLISYDRYQSVSNAVRYRAQHTGILKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTEECEPGFVTEWYILAITAFLEFLLPVSLVVYFSVQIYWSLWKRGSLSRCPSHAGFIATSSRGTGHSRRTGLACRTSLPGLKEPAASLHSESPRGKSSLLVSLRTHMSGSIIAFKVGSFCRSESPVLHQREHVELLRGRKLARSLAVLLSAFAICWAPYCLFTIVLSTYRRGERPKSIWYSIAFWLQWFNSLINPFLYPLCHRRFQKAFWKILCVTKQPAPSQTQSVSS
UniProt	Q91ZY1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4468
IUPHAR	265
DrugBank	N/A

Ligand

Name	Z-cinnamyl alcohol
Molecular formula	C9H10O
IUPAC name	(Z)-3-phenylprop-2-en-1-ol
Molecular weight	134.178
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	1.9
Synonyms	SCHEMBL891462 (Z)-3-Phenyl-2-propen-1-ol 3-Phenyl-2-propenol Cinnamyl alcohol, (Z)- I01-6177 ZINC4623761 .gamma.-Phenylallyl alcohol Alkohol skoricovy OT636Q443X 2-Propen-1-ol, 3-phenyl-, (Z)- CHEMBL118958 UNII-OT636Q443X (Z)-3-phenylprop-2-en-1-ol 4510-34-3 cis-cinnamyl alcohol OOCCDEMITAIZTP-DAXSKMNVSA-N 1-Phenyl-1-propen-3-ol CHEBI:33226 Phenylallyl alcohol (2Z)-3-phenylprop-2-en-1-ol 3-Fenyl-2-propen-1-ol Cinnamyl Alcohol Natural (Z)-cinnamyl alcohol AC1NQX4S CS-12674 OOCCDEMITAIZTP-UHFFFAOYSA-N 2-Propen-1-ol, 3-phenyl- [ Show all ]
Inchi Key	OOCCDEMITAIZTP-DAXSKMNVSA-N
Inchi ID	InChI=1S/C9H10O/c10-8-4-7-9-5-2-1-3-6-9/h1-7,10H,8H2/b7-4-
PubChem CID	5280511
ChEMBL	CHEMBL118958
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	4.3 %	PMID12443776	ChEMBL

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