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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Mus musculus (Mouse)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
UniProt	P30557
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4336
IUPHAR	342
DrugBank	N/A

Ligand

Name	CHEMBL185369
Molecular formula	C25H29NO5
IUPAC name	4-[1-(4-butoxybenzoyl)-5-methoxy-2-methylindol-3-yl]butanoic acid
Molecular weight	423.509
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.5
Synonyms	4-[1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butyric acid BDBM50150972
Inchi Key	OGNGNXGCXSFDBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29NO5/c1-4-5-15-31-19-11-9-18(10-12-19)25(29)26-17(2)21(7-6-8-24(27)28)22-16-20(30-3)13-14-23(22)26/h9-14,16H,4-8,15H2,1-3H3,(H,27,28)
PubChem CID	11418818
ChEMBL	CHEMBL185369
IUPHAR	N/A
BindingDB	50150972
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2400.0 nM	PMID15357992	BindingDB,ChEMBL

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