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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1D
Species	Cavia porcellus (Guinea pig)
Gene	HTR1D
Synonym	5-HT-1D 5-HT1D Serotonin receptor 1D
Disease	N/A for non-human GPCRs
Length	376
Amino acid sequence	MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFTTAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATKTLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEDFRQAFQKVVHFRKAS
UniProt	Q60484
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304407
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL309021
Molecular formula	C24H27N3O2
IUPAC name	3-[3-(dimethylamino)propyl]-4-methoxy-N-(4-pyridin-4-ylphenyl)benzamide
Molecular weight	389.499
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.9
Synonyms	3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-4-yl-phenyl)-benzamide BDBM50060518 L011871 3-[3-(Dimethylamino)propyl]-4-methoxy-N-[4-(4-pyridinyl)phenyl]benzamide
Inchi Key	OARBZUBLNNFTMQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)
PubChem CID	10068933
ChEMBL	CHEMBL309021
IUPHAR	N/A
BindingDB	50060518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	>30.0 %	PMID8057272	ChEMBL
Ki	10.0 nM	PMID8057272	ChEMBL

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