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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Delta-type opioid receptor
Species	Rattus norvegicus (Rat)
Gene	Oprd1
Synonym	opioid receptor OP1 DOR-1 DOR DOPr DOP delta receptor D-OR-1 Opioid receptor A [ Show all ]
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
UniProt	P33533
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL269
IUPHAR	317
DrugBank	N/A

Ligand

Name	CHEMBL346163
Molecular formula	C16H23NO
IUPAC name	3-[1-(cyclopropylmethyl)-3-methylpiperidin-3-yl]phenol
Molecular weight	245.366
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.4
Synonyms	3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-phenol:hydrochloricacid 3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-phenol BDBM50021324
Inchi Key	BFJGDYASFRFDRK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H23NO/c1-16(14-4-2-5-15(18)10-14)8-3-9-17(12-16)11-13-6-7-13/h2,4-5,10,13,18H,3,6-9,11-12H2,1H3
PubChem CID	13615888
ChEMBL	CHEMBL346163
IUPHAR	N/A
BindingDB	50021324
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	2700.0 nM	PMID3007760	BindingDB,ChEMBL
Kd	4350.0 nM	PMID3007760	BindingDB,ChEMBL

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