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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Chlorocebus aethiops (Green monkey)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSKIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRSHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKNHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	P52702
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5456
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL538503
Molecular formula	C20H22BrN3O2
IUPAC name	N-[[2-(5-bromo-2,3-dimethoxyphenyl)-1H-imidazol-5-yl]methyl]-N-methyl-1-phenylmethanamine
Molecular weight	416.319
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50035384 2-(2,3-Dimethoxy-5-bromophenyl)-5-[(N-benzyl-N-methylamino)methyl]-1H-imidazole Benzyl-[2-(5-bromo-2,3-dimethoxy-phenyl)-3H-imidazol-4-ylmethyl]-methyl-amine; dihydrochloride L013621 CHEMBL1189316
Inchi Key	NDIHRQSUWICICR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22BrN3O2/c1-24(12-14-7-5-4-6-8-14)13-16-11-22-20(23-16)17-9-15(21)10-18(25-2)19(17)26-3/h4-11H,12-13H2,1-3H3,(H,22,23)
PubChem CID	10319701
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50035384
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	0.7 nM	PMID7783157	BindingDB

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