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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 1
Species	Meleagris gallopavo (Wild turkey)
Gene	P2RY1
Synonym	6H1 orphan receptor ADP receptor P2Y1 Purinergic receptor
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProt	P49652
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5720
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3085531
Molecular formula	C13H18ClN5O8P2
IUPAC name	[(1R,2R,4S,5S)-4-[2-chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
Molecular weight	469.712
Hydrogen bond acceptor	12
Hydrogen bond donor	5
XlogP	-1.6
Synonyms	BDBM50026893
Inchi Key	NDCFGYFBDZLTJB-LJYOZPSBSA-N
Inchi ID	InChI=1S/C13H18ClN5O8P2/c1-15-10-9-11(18-12(14)17-10)19(5-16-9)7-2-8(27-29(23,24)25)13(3-6(7)13)4-26-28(20,21)22/h5-8H,2-4H2,1H3,(H,15,17,18)(H2,20,21,22)(H2,23,24,25)/t6-,7+,8-,13+/m1/s1
PubChem CID	76324375
ChEMBL	CHEMBL3085531
IUPHAR	N/A
BindingDB	50026893
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
EC50	52.0 nM	PMID12213051	BindingDB,ChEMBL
IC50	51.6 nM	PMID10715151	ChEMBL
IC50	52.0 nM	PMID11754592	ChEMBL
Max inhibition	100.0 %	PMID10715151	ChEMBL

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