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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 182
Species	Homo sapiens (Human)
Gene	GPR182
Synonym	NOW L1-R GPR182 Gpcr22 Gpcr17 adrenomedullin receptor ADMR [ Show all ]
Disease	N/A
Length	404
Amino acid sequence	MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
UniProt	O15218
Protein Data Bank	N/A
GPCR-HGmod model	O15218
3D structure model	This predicted structure model is from GPCR-EXP O15218.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4356
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	NSC697161
Molecular formula	C26H32Cl2N8O2
IUPAC name	3-[8-[4-amino-5-[(4-chlorophenoxy)methyl]-1,2,4-triazol-3-yl]octyl]-5-[(4-chlorophenoxy)methyl]-1,2,4-triazol-4-amine
Molecular weight	559.496
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.9
Synonyms	AC1L97G1 CTK8C9698 3-(8-(4-Amino-5-((4-chlorophenoxy)methyl)-4H-1,2,4-triazol-3-yl)octyl)-5-((4-chlorophenoxy)methyl)-4H-1,2,4-triazol-4-ylamine NCI60_034630 3-[8-[4-amino-5-[(4-chlorophenoxy)methyl]-1,2,4-triazol-3-yl]octyl]-5-[(4-chlorophenoxy)methyl]-1,2,4-triazol-4-amine CHEMBL195841 3,3'-octane-1,8-diylbis{5-[(4-chlorophenoxy)methyl]-4h-1,2,4-triazol-4-amine} NSC-697161 [ Show all ]
Inchi Key	NASDCQVYKOBYIL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H32Cl2N8O2/c27-19-9-13-21(14-10-19)37-17-25-33-31-23(35(25)29)7-5-3-1-2-4-6-8-24-32-34-26(36(24)30)18-38-22-15-11-20(28)12-16-22/h9-16H,1-8,17-18,29-30H2
PubChem CID	394043
ChEMBL	CHEMBL195841
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Affinity	19.0 %	PMID15943480	ChEMBL

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