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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H2 receptor
Species	Mus musculus (Mouse)
Gene	Hrh2
Synonym	Gastric receptor I H2 receptor H2R HH2R
Disease	N/A for non-human GPCRs
Length	397
Amino acid sequence	MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQLFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTRLSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA
UniProt	P97292
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2245
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	NSC669715
Molecular formula	C11H21N3
IUPAC name	N-[2-(1H-imidazol-5-yl)ethyl]hexan-1-amine
Molecular weight	195.31
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	2.1
Synonyms	CHEMBL69530 2-(1H-Imidazol-4-yl)-N-hexylethanamine N-[2-(1H-imidazol-5-yl)ethyl]hexan-1-amine AKOS014566605 103827-09-4 N-(2-(1H-Imidazol-4-yl)ethyl)-1-hexanamine hydrochloride AC1L8IYJ NCI60_024373 1H-Imidazole-5-ethanamine, N-hexyl- N-[2-(1H-imidazol-4-yl)ethyl]hexan-1-amine AC1Q4WOL [ Show all ]
Inchi Key	MXLOXTMJEAHTMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H21N3/c1-2-3-4-5-7-12-8-6-11-9-13-10-14-11/h9-10,12H,2-8H2,1H3,(H,13,14)
PubChem CID	382262
ChEMBL	CHEMBL69530
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Relative potency	5.0 -	PMID2959777	ChEMBL

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