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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL3610842
Molecular formula	C9H7F3N2O
IUPAC name	(4S)-4-(3,4,5-trifluorophenyl)-4,5-dihydro-1,3-oxazol-2-amine
Molecular weight	216.163
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.2
Synonyms	CHEMBL3684793 BDBM109443
Inchi Key	BEKYPYLXHFMSDA-SSDOTTSWSA-N
Inchi ID	InChI=1S/C9H7F3N2O/c10-5-1-4(2-6(11)8(5)12)7-3-15-9(13)14-7/h1-2,7H,3H2,(H2,13,14)/t7-/m1/s1
PubChem CID	24966464
ChEMBL	CHEMBL3684793
IUPHAR	N/A
BindingDB	109443
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.1 nM	, None	BindingDB,ChEMBL

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