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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Sstr1
Synonym	SRIF-2 SS-1-R SS1-R SS1R SST1 receptor
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
UniProt	P28646
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4652
IUPHAR	355
DrugBank	N/A

Ligand

Name	CHEMBL251752
Molecular formula	C27H32N4O4
IUPAC name	1-[(3R,4aR,10aR)-1-methyl-3-[4-(4-nitrophenyl)piperazine-1-carbonyl]-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-6-yl]ethanone
Molecular weight	476.577
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.3
Synonyms	BDBM50423318
Inchi Key	MWGZIXFRKZVJAV-IPVFLDMMSA-N
Inchi ID	InChI=1S/C27H32N4O4/c1-18(32)24-5-3-4-19-16-26-20(15-25(19)24)14-21(17-28(26)2)27(33)30-12-10-29(11-13-30)22-6-8-23(9-7-22)31(34)35/h3-9,20-21,26H,10-17H2,1-2H3/t20-,21-,26-/m1/s1
PubChem CID	44441668
ChEMBL	CHEMBL251752
IUPHAR	N/A
BindingDB	50423318
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	6.0 nM	PMID17507221	BindingDB
Kd	6.026 nM	PMID17507221	ChEMBL

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