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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1830278
Molecular formula	C13H17ClN2O2
IUPAC name	(4S)-4-[(2S)-2-(3-chlorophenoxy)butyl]-4,5-dihydro-1,3-oxazol-2-amine
Molecular weight	268.741
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.9
Synonyms	US8729113, 112 CHEMBL3652752 BDBM122364
Inchi Key	BEEXOKZWBRZYAE-QWRGUYRKSA-N
Inchi ID	InChI=1S/C13H17ClN2O2/c1-2-11(7-10-8-17-13(15)16-10)18-12-5-3-4-9(14)6-12/h3-6,10-11H,2,7-8H2,1H3,(H2,15,16)/t10-,11-/m0/s1
PubChem CID	45100816
ChEMBL	CHEMBL3652752
IUPHAR	N/A
BindingDB	122364
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.2 nM	, None	BindingDB,ChEMBL

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